Impaired spike-gamma coupling of area CA3 fast-spiking interneurons as the earliest functional impai...
Impaired spike-gamma coupling of area CA3 fast-spiking interneurons as the earliest functional impairment in the App.sup.NL-G-F mouse model of Alzheimer's disease
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Nature Publishing Group
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English
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Nature Publishing Group
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In Alzheimer's disease (AD) the accumulation of amyloid-[beta] (A[beta]) correlates with degradation of cognition-relevant gamma oscillations. The gamma rhythm relies on proper neuronal spike-gamma coupling, specifically of fast-spiking interneurons (FSN). Here we tested the hypothesis that decrease in gamma power and FSN synchrony precede amyloid...
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Impaired spike-gamma coupling of area CA3 fast-spiking interneurons as the earliest functional impairment in the App.sup.NL-G-F mouse model of Alzheimer's disease
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TN_cdi_gale_infotracmisc_A691095349
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A691095349
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1359-4184
DOI
10.1038/s41380-021-01257-0
