A dual role of HIF1[alpha] in regulating osteogenesis-angiogenesis coupling
A dual role of HIF1[alpha] in regulating osteogenesis-angiogenesis coupling
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Publisher
BioMed Central Ltd
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Language
English
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BioMed Central Ltd
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Contents
Objectives The hypoxia-inducible factor 1-[alpha] (HIF1[alpha]), a key molecule in mediating bone-vessel crosstalk, has been considered a promising target for treating osteoporosis caused by gonadal hormones. However, senile osteoporosis, with accumulated senescent cells in aged bone, has a distinct pathogenesis. The study aimed at revealing the un...
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Full title
A dual role of HIF1[alpha] in regulating osteogenesis-angiogenesis coupling
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TN_cdi_gale_infotracmisc_A693686618
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A693686618
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-022-02742-1
