Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stres...
Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor
About this item
Full title
Author / Creator
Godsel, Lisa M , Roth-Carter, Quinn R , Koetsier, Jennifer L , Tsoi, Lam C , Huffine, Amber L , Broussard, Joshua A , Fitz, Gillian N , Lloyd, Sarah M , Kweon, Junghun , Burks, Hope E , Hegazy, Marihan , Amagai, Saki , Harms, Paul W , Xing, Xianying , Kirma, Joseph , Johnson, Jodi L , Urciuoli, Gloria , Doglio, Lynn T , Swindell, William R , Awatramani, Rajeshwar , Sprecher, Eli , Bao, Xiaomin , Cohen-Barak, Eran , Missero, Caterina , Gudjonsson, Johann E and Green, Kathleen J
Publisher
American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Desmoglein 1 (Dsg1) is a cadherin restricted to stratified tissues of terrestrial vertebrates, which serve as essential physical and immune barriers. Dsg1 loss-of-function mutations in humans result in skin lesions and multiple allergies, and isolated patient keratinocytes exhibit increased proallergic cytokine expression. However, the mechanism by...
Alternative Titles
Full title
Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor
Authors, Artists and Contributors
Author / Creator
Roth-Carter, Quinn R
Koetsier, Jennifer L
Tsoi, Lam C
Huffine, Amber L
Broussard, Joshua A
Fitz, Gillian N
Lloyd, Sarah M
Kweon, Junghun
Burks, Hope E
Hegazy, Marihan
Amagai, Saki
Harms, Paul W
Xing, Xianying
Kirma, Joseph
Johnson, Jodi L
Urciuoli, Gloria
Doglio, Lynn T
Swindell, William R
Awatramani, Rajeshwar
Sprecher, Eli
Bao, Xiaomin
Cohen-Barak, Eran
Missero, Caterina
Gudjonsson, Johann E
Green, Kathleen J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A693733729
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A693733729
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI144363.
