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Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangi...

Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A693733738

Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

About this item

Full title

Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Publisher

American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022-02, Vol.132 (3)

Language

English

Formats

Publication information

Publisher

American Society for Clinical Investigation

More information

Scope and Contents

Contents

Propranolol and atenolol, current therapies for problematic infantile hemangioma (IH), are composed of R(+) and S(-) enantiomers: the R(+) enantiomer is largely devoid of beta blocker activity. We investigated the effect of R(+) enantiomers of propranolol and atenolol on the formation of IH-like blood vessels from hemangioma stem cells (HemSCs) in...

Alternative Titles

Full title

Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A693733738

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A693733738

Other Identifiers

ISSN

0021-9738

DOI

10.1172/JCI151109.

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