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Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3.sup.ATR kinas...

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3.sup.ATR kinas...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A702224852

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3.sup.ATR kinase is essential in the absence of Rqh1.sup.BLM helicase

About this item

Full title

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3.sup.ATR kinase is essential in the absence of Rqh1.sup.BLM helicase

Publisher

Public Library of Science

Journal title

PLoS genetics, 2022-04, Vol.18 (4), p.e1010165

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

The Mus81-Eme1 structure-specific endonuclease is crucial for the processing of DNA recombination and late replication intermediates. In fission yeast, stimulation of Mus81-Eme1 in response to DNA damage at the G2/M transition relies on Cdc2.sup.CDK1 and DNA damage checkpoint-dependent phosphorylation of Eme1 and is critical for chromosome stabilit...

Alternative Titles

Full title

Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3.sup.ATR kinase is essential in the absence of Rqh1.sup.BLM helicase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A702224852

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A702224852

Other Identifiers

ISSN

1553-7390

DOI

10.1371/journal.pgen.1010165

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