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Synthesis, Pass Predication of Antimicrobial Activity and Pharmacokinetic Properties of Hexanoyl Gal...

Synthesis, Pass Predication of Antimicrobial Activity and Pharmacokinetic Properties of Hexanoyl Gal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A716037728

Synthesis, Pass Predication of Antimicrobial Activity and Pharmacokinetic Properties of Hexanoyl Galactopyranosides and Experimental Evaluation of their Action against Four Human Pathogenic Bacteria and Four Fungal Strains

About this item

Full title

Synthesis, Pass Predication of Antimicrobial Activity and Pharmacokinetic Properties of Hexanoyl Galactopyranosides and Experimental Evaluation of their Action against Four Human Pathogenic Bacteria and Four Fungal Strains

Publisher

New York: Springer US

Journal title

Pharmaceutical chemistry journal, 2022-08, Vol.56 (5), p.627-637

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Direct unimolar hexanoylation of methyl α-D-galactopyranoside (MDG) at low temperature gave 6-
O
-hexanoate in 53% yield indicating regioselectivity at the C-6 position. To develop galctopyranoside-based potential antimicrobial sugar esters (SEs), 6-
O
-hexanoate was further converted into seven new 2,3,4-tri-
O
-acyl esters in re...

Alternative Titles

Full title

Synthesis, Pass Predication of Antimicrobial Activity and Pharmacokinetic Properties of Hexanoyl Galactopyranosides and Experimental Evaluation of their Action against Four Human Pathogenic Bacteria and Four Fungal Strains

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A716037728

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A716037728

Other Identifiers

ISSN

0091-150X

E-ISSN

1573-9031

DOI

10.1007/s11094-022-02687-y

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