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Synthesis and Biological Evaluation of Cassane Diterpene -Diene and of Some Related Compounds

Synthesis and Biological Evaluation of Cassane Diterpene -Diene and of Some Related Compounds

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A725109648

Synthesis and Biological Evaluation of Cassane Diterpene -Diene and of Some Related Compounds

About this item

Full title

Synthesis and Biological Evaluation of Cassane Diterpene -Diene and of Some Related Compounds

Publisher

MDPI AG

Journal title

Molecules (Basel, Switzerland), 2022-09, Vol.27 (17)

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

A set of thirteen cassane-type diterpenes was synthesized and an expedient synthetic route was used to evaluate 14-desmethyl analogs of the most active tested cassane. The anti-inflammatory activities of these 13 compounds were evaluated on a lipopolysaccharide (LPS)-activated RAW 264.7 cell line by inhibition of nitric oxide (NO) production, some...

Alternative Titles

Full title

Synthesis and Biological Evaluation of Cassane Diterpene -Diene and of Some Related Compounds

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A725109648

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A725109648

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules27175705

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