Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity
Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity
Publication information
Publisher
Springer Spektrum
Subjects
More information
Scope and Contents
Contents
Drug-induced neurotoxicity is a leading cause of safety-related attrition for therapeutics in clinical trials, often driven by poor predictivity of preclinical in vitro and in vivo models of neurotoxicity. Over a dozen different iPSC- derived 3D spheroids have been described in recent years, but their ability to predict neurotoxicity in patients ha...
Alternative Titles
Full title
Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A729115083
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A729115083
Other Identifiers
ISSN
1868-596X
E-ISSN
1868-596X
DOI
10.14573/altex.2112221