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Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma...

Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A729280648

Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?

About this item

Full title

Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Liver cancer (Basel ), 2022-12, Vol.11 (6), p.540-557

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Abstract
Introduction: Heparin sulphate proteoglycans in the liver tumour microenvironment (TME) are key regulators of cell signalling, modulated by sulfatase-2 (SULF2). SULF2 overexpression occurs in hepatocellular carcinoma (HCC). Our aims were to define the nature and impact of SULF2 in the HCC TME. Methods: In liver biopsies from 60 patients...

Alternative Titles

Full title

Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A729280648

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A729280648

Other Identifiers

ISSN

2235-1795

E-ISSN

1664-5553

DOI

10.1159/000525375

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