Opposing effects of [beta]-2 and [beta]-1 adrenergic receptor signaling on neuroinflammation and dop...
Opposing effects of [beta]-2 and [beta]-1 adrenergic receptor signaling on neuroinflammation and dopaminergic neuron survival in [alpha]-synuclein-mediated neurotoxicity
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Background Noradrenergic neurons in the locus coeruleus (LC) are the primary source of norepinephrine (NE) in the brain and degeneration of these neurons is reported in the early stages of Parkinson's disease (PD), even prior to dopaminergic neuron degeneration in the substantia nigra (SN), which is a hallmark of PD pathology. NE depletion is gener...
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Full title
Opposing effects of [beta]-2 and [beta]-1 adrenergic receptor signaling on neuroinflammation and dopaminergic neuron survival in [alpha]-synuclein-mediated neurotoxicity
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TN_cdi_gale_infotracmisc_A739377191
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A739377191
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02748-3
