Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup....
Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup.2+] and Oxaliplatin-Associated Pt[sup.2+]
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MDPI AG
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English
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MDPI AG
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Disappointing results from the POLAR A and M phase III trials involving colorectal cancer patients on chemotherapy with FOLFOX6 in curative (A) and palliative (M) settings have been reported by the principal investigators and the sponsor (PledPharma AB/Egetis Therapeutics AB). FOLFOX6, oxaliplatin in combination with 5-fluorouracil (5-FU), possesse...
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Full title
Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup.2+] and Oxaliplatin-Associated Pt[sup.2+]
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TN_cdi_gale_infotracmisc_A743462062
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A743462062
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ISSN
2076-3921
E-ISSN
2076-3921
DOI
10.3390/antiox12030608