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Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup....

Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup....

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A743462062

Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup.2+] and Oxaliplatin-Associated Pt[sup.2+]

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Full title

Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup.2+] and Oxaliplatin-Associated Pt[sup.2+]

Publisher

MDPI AG

Journal title

Antioxidants, 2023-03, Vol.12 (3)

Language

English

Formats

Publication information

Publisher

MDPI AG

Subjects

More information

Scope and Contents

Contents

Disappointing results from the POLAR A and M phase III trials involving colorectal cancer patients on chemotherapy with FOLFOX6 in curative (A) and palliative (M) settings have been reported by the principal investigators and the sponsor (PledPharma AB/Egetis Therapeutics AB). FOLFOX6, oxaliplatin in combination with 5-fluorouracil (5-FU), possesse...

Alternative Titles

Full title

Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn[sup.2+] and Oxaliplatin-Associated Pt[sup.2+]

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A743462062

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A743462062

Other Identifiers

ISSN

2076-3921

E-ISSN

2076-3921

DOI

10.3390/antiox12030608

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