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Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Ex...

Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Ex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A744516915

Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C T Mutation in the Breast Cancer Predisposing Gene IPALB2/I

About this item

Full title

Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C T Mutation in the Breast Cancer Predisposing Gene IPALB2/I

Publisher

MDPI AG

Journal title

Epigenomes, 2022-09, Vol.6 (4)

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

Background: Deregulation of DNA methylation/demethylation reactions may be the source of C > T mutation via active deamination of 5-methylcytosine to thymine. Exposome, that is to say, the totality of exposures to which an individual is subjected during their life, can deregulate these reactions. Thus, one may wonder whether the exposome can induce...

Alternative Titles

Full title

Modulation of DNA Methylation/Demethylation Reactions Induced by Nutraceuticals and Pollutants of Exposome Can Promote a C T Mutation in the Breast Cancer Predisposing Gene IPALB2/I

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A744516915

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A744516915

Other Identifiers

ISSN

2075-4655

E-ISSN

2075-4655

DOI

10.3390/epigenomes6040032

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