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Secretory Leucoprotease Inhibitor Promotes Survival during Acute IPseudomonas aeruginosa/I Infection...

Secretory Leucoprotease Inhibitor Promotes Survival during Acute IPseudomonas aeruginosa/I Infection...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A745221216

Secretory Leucoprotease Inhibitor Promotes Survival during Acute IPseudomonas aeruginosa/I Infection by Suppression of Inflammation Rather Than Microbial Killing

About this item

Full title

Secretory Leucoprotease Inhibitor Promotes Survival during Acute IPseudomonas aeruginosa/I Infection by Suppression of Inflammation Rather Than Microbial Killing

Publisher

MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2022-11, Vol.12 (12)

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

Secretory leucoprotease inhibitor (SLPI) has multifaceted functions, including inhibition of protease activity, antimicrobial functions, and anti-inflammatory properties. In this study, we show that SLPI plays a role in controlling pulmonary Pseudomonas aeruginosa infection. Mice lacking SLPI were highly susceptible to P. aeruginosa infection, howe...

Alternative Titles

Full title

Secretory Leucoprotease Inhibitor Promotes Survival during Acute IPseudomonas aeruginosa/I Infection by Suppression of Inflammation Rather Than Microbial Killing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A745221216

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A745221216

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom12121728

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