Statins Induce Locomotion and Muscular Phenotypes in IDrosophila melanogaster/I That Are Reminiscent...
Statins Induce Locomotion and Muscular Phenotypes in IDrosophila melanogaster/I That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
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Author / Creator
Al-Sabri, Mohamed H , Behare, Neha , Alsehli, Ahmed M , Berkins, Samuel , Arora, Aadeya , Antoniou, Eirini , Moysiadou, Eleni I , Anantha-Krishnan, Sowmya , Cosmen, Patricia D , Vikner, Johanna , Moulin, Thiago C , Ammar, Nourhene , Boukhatmi, Hadi , Clemensson, Laura E , Rask-Andersen, Mathias , Mwinyi, Jessica , Williams, Michael J , Fredriksson, Robert and Schiöth, Helgi B
Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
The underlying mechanisms for statin-induced myopathy (SIM) are still equivocal. In this study, we employ Drosophila melanogaster to dissect possible underlying mechanisms for SIM. We observe that chronic fluvastatin treatment causes reduced general locomotion activity and climbing ability. In addition, transmission microscopy of dissected skeletal...
Alternative Titles
Full title
Statins Induce Locomotion and Muscular Phenotypes in IDrosophila melanogaster/I That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
Authors, Artists and Contributors
Author / Creator
Behare, Neha
Alsehli, Ahmed M
Berkins, Samuel
Arora, Aadeya
Antoniou, Eirini
Moysiadou, Eleni I
Anantha-Krishnan, Sowmya
Cosmen, Patricia D
Vikner, Johanna
Moulin, Thiago C
Ammar, Nourhene
Boukhatmi, Hadi
Clemensson, Laura E
Rask-Andersen, Mathias
Mwinyi, Jessica
Williams, Michael J
Fredriksson, Robert
Schiöth, Helgi B
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A745410705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A745410705
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11223528
