Characterization of Sigma-2 Receptor—Specific Binding Sites Using [[sup.3]H]DTG and [[sup.125]I]RHM-...
Characterization of Sigma-2 Receptor—Specific Binding Sites Using [[sup.3]H]DTG and [[sup.125]I]RHM-4
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Publisher
MDPI AG
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Language
English
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MDPI AG
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Contents
The sigma-2 receptor/transmembrane protein 97 (σ2R/TMRM97) is a promising biomarker of tumor proliferation and a target for cancer therapy. [[sup.3] H]DTG has been used to evaluate σ2R/TMEM97 binding affinity in compound development studies. However, [[sup.3] H]DTG has equal and moderate binding affinities to both sigma 1 receptor (σ1R) and σ2R/TME...
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Full title
Characterization of Sigma-2 Receptor—Specific Binding Sites Using [[sup.3]H]DTG and [[sup.125]I]RHM-4
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TN_cdi_gale_infotracmisc_A746370633
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A746370633
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph15121564
