Guanidines: Synthesis of Novel Histamine H[sub.3]R Antagonists with Additional Breast Anticancer Act...
Guanidines: Synthesis of Novel Histamine H[sub.3]R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect
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Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
This study examines the properties of novel guanidines, designed and synthesized as histamine H[sub.3] R antagonists/inverse agonists with additional pharmacological targets. We evaluated their potential against two targets viz., inhibition of MDA-MB-231, and MCF-7 breast cancer cells viability and inhibition of AChE/BuChE. ADS10310 showed micromol...
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Full title
Guanidines: Synthesis of Novel Histamine H[sub.3]R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect
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TN_cdi_gale_infotracmisc_A750993714
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A750993714
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph16050675
