An open protocol for modeling T Cell Clonotype repertoires using TCR[beta] CDR3 sequences
An open protocol for modeling T Cell Clonotype repertoires using TCR[beta] CDR3 sequences
About this item
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Author / Creator
Publisher
BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
BioMed Central Ltd
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More information
Scope and Contents
Contents
T cell receptor repertoires can be profiled using next generation sequencing (NGS) to measure and monitor adaptive dynamical changes in response to disease and other perturbations. Genomic DNA-based bulk sequencing is cost-effective but necessitates multiplex target amplification using multiple primer pairs with highly variable amplification effici...
Alternative Titles
Full title
An open protocol for modeling T Cell Clonotype repertoires using TCR[beta] CDR3 sequences
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A754838155
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A754838155
Other Identifiers
ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-023-09424-z
