Synthesis, [sup.123]I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-B...
Synthesis, [sup.123]I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
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Author / Creator
Hasnowo, Lutfi A , Larkina, Maria S , Plotnikov, Evgenii , Bodenko, Vitalina , Yuldasheva, Feruza , Stasyuk, Elena , Petrov, Stanislav A , Zyk, Nikolai Y , Machulkin, Aleksei E , Vorozhtsov, Nikolai I , Beloglazkina, Elena K , Nenajdenko, Valentine G , Tolmachev, Vladimir , Orlova, Anna , Majouga, Alexander G and Yusubov, Mekhman S
Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
Prostate-specific membrane antigen (PSMA) has been identified as a target for the development of theranostic agents. In our current work, we describe the design and synthesis of novel N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-(S)-L-lysine (DCL) urea-based PSMA inhibitors with a chlorine-substituted aromatic fragment at the lysine ε-nitrogen atom, a...
Alternative Titles
Full title
Synthesis, [sup.123]I-Radiolabeling Optimization, and Initial Preclinical Evaluation of Novel Urea-Based PSMA Inhibitors with a Tributylstannyl Prosthetic Group in Their Structures
Authors, Artists and Contributors
Author / Creator
Larkina, Maria S
Plotnikov, Evgenii
Bodenko, Vitalina
Yuldasheva, Feruza
Stasyuk, Elena
Petrov, Stanislav A
Zyk, Nikolai Y
Machulkin, Aleksei E
Vorozhtsov, Nikolai I
Beloglazkina, Elena K
Nenajdenko, Valentine G
Tolmachev, Vladimir
Orlova, Anna
Majouga, Alexander G
Yusubov, Mekhman S
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A760515737
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A760515737
Other Identifiers
ISSN
1422-0067
DOI
10.3390/ijms241512206
