Domino Aldol-S[sub.N]Ar-Dehydration Sequence for [3+3] Annulations to Prepare Quinolin-2-ones
Domino Aldol-S[sub.N]Ar-Dehydration Sequence for [3+3] Annulations to Prepare Quinolin-2-ones
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Author / Creator
Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
A domino aldol-S[sub.N]Ar-dehydration [3+3] annulation strategy has been utilized to fuse six-membered cyclic amides onto aromatic substrates. 2-Arylacetamides have been reacted with 2-fluorobenzaldehyde derivatives activated toward S[sub.N]Ar reaction by an electron-withdrawing substituent (NO[sub.2], CN, CF[sub.3], CO[sub.2]Me) at C5 to prepare 3...
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Full title
Domino Aldol-S[sub.N]Ar-Dehydration Sequence for [3+3] Annulations to Prepare Quinolin-2-ones
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Author / Creator
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Record Identifier
TN_cdi_gale_infotracmisc_A760517064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A760517064
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28155856
