Supraphysiologic doses of 17[beta]-estradiol aggravate depression-like behaviors in ovariectomized m...
Supraphysiologic doses of 17[beta]-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism
About this item
Full title
Author / Creator
Li, Ming , Zhang, Jing , Chen, Wendi , Liu, Shuang , Liu, Xin , Ning, Yunna , Cao, Yongzhi and Zhao, Yueran
Publisher
BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Background 17[beta]-Estradiol (E2) is generally considered neuroprotective in humans. However, the current clinical use of estrogen replacement therapy (ERT) is based on the physiological dose of E2 to treat menopausal syndrome and has limited therapeutic efficacy. The efficacy and potential toxicity of superphysiological doses of ERT for menopausa...
Alternative Titles
Full title
Supraphysiologic doses of 17[beta]-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A763994124
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A763994124
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02889-5
