Phenotype screens of murine pancreatic cancer identify a Tgf-[alpha]-Ccl2-paxillin axis driving huma...
Phenotype screens of murine pancreatic cancer identify a Tgf-[alpha]-Ccl2-paxillin axis driving human-like neural invasion
About this item
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Author / Creator
Wang, Xiaobo , Istvanffy, Rouzanna , Ye, Linhan , Teller, Steffen , Laschinger, Melanie , Diakopoulos, Kalliope N , Gorgulu, Kivanc , Li, Qiaolin , Ren, Lei , Jager, Carsten , Steiger, Katja , Muckenhuber, Alexander , Vilne, Baiba , Cifcibasi, Kaan , Reyes, Carmen Mota , Yurteri, Ummugulsum , Kiessler, Maximilian , Gurcinar, Ibrahim Halil , Sugden, Maya , Yildizhan, Saliha Elif , Sezerman, Osman Ugur , Cilingir, Sumeyye , Suyen, Guldal , Reichert, Maximilian , Schmid, Roland M , Barthel, Stefanie , Oellinger, Rupert , Kruger, Achim , Rad, Roland , Saur, Dieter , Algul, Hana , Friess, Helmut , Lesina, Marina , Ceyhan, Guralp Onur and Demir, Ihsan Ekin
Publisher
American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Solid cancers like pancreatic ductal adenocarcinoma (PDAC), a type of pancreatic cancer, frequently exploit nerves for rapid dissemination. This neural invasion (NI) is an independent prognostic factor in PDAC, but insufficiently modeled in genetically engineered mouse models (GEMM) of PDAC. Here, we systematically screened for human-like NI in Eur...
Alternative Titles
Full title
Phenotype screens of murine pancreatic cancer identify a Tgf-[alpha]-Ccl2-paxillin axis driving human-like neural invasion
Authors, Artists and Contributors
Author / Creator
Istvanffy, Rouzanna
Ye, Linhan
Teller, Steffen
Laschinger, Melanie
Diakopoulos, Kalliope N
Gorgulu, Kivanc
Li, Qiaolin
Ren, Lei
Jager, Carsten
Steiger, Katja
Muckenhuber, Alexander
Vilne, Baiba
Cifcibasi, Kaan
Reyes, Carmen Mota
Yurteri, Ummugulsum
Kiessler, Maximilian
Gurcinar, Ibrahim Halil
Sugden, Maya
Yildizhan, Saliha Elif
Sezerman, Osman Ugur
Cilingir, Sumeyye
Suyen, Guldal
Reichert, Maximilian
Schmid, Roland M
Barthel, Stefanie
Oellinger, Rupert
Kruger, Achim
Rad, Roland
Saur, Dieter
Algul, Hana
Friess, Helmut
Lesina, Marina
Ceyhan, Guralp Onur
Demir, Ihsan Ekin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A771908780
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A771908780
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI166333
