Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synovioc...
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/[beta]-catenin pathway
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Author / Creator
Guo, Dong , Pan, Haoyan , Lu, Xueying , Chen, Zhong , Zhou, Laixi , Chen, Shuxin , Huang, Jin , Liang, Xinzhi , Xiao, Zhisheng , Zeng, Hua , Shao, Yan , Qi, Weizhong , Xie, Denghui and Lin, Chuangxin
Publisher
BioMed Central Ltd
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Language
English
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Publisher
BioMed Central Ltd
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Background The aggressive phenotype of fibroblast-like synoviocytes (FLS) has been identified as a contributing factor to the exacerbation of rheumatoid arthritis (RA) through the promotion of synovitis and cartilage damage. Regrettably, there is currently no effective therapeutic intervention available to address this issue. Recent research has sh...
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Full title
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/[beta]-catenin pathway
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TN_cdi_gale_infotracmisc_A772249562
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A772249562
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ISSN
1478-6354
DOI
10.1186/s13075-023-03198-1
