Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications
Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications
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Publisher
Oxford University Press
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Language
English
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Oxford University Press
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Contents
[alpha]-Ketoglutarate ([alpha]KG)-dependent dioxygenases are a superfamily of enzymes that require oxygen, reduced iron, and [alpha]KG for their catalytic functions. Therefore, they have the potential to sense the availabilities of oxygen, iron, and specific metabolites, including [alpha]KG and its structurally related metabolites. These enzymes pl...
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Full title
Ketoglutarate-dependent Enzymes in Breast Cancer and Therapeutic Implications
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TN_cdi_gale_infotracmisc_A775899411
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A775899411
Other Identifiers
ISSN
0013-7227
DOI
10.1210/endocr/bad080
