Acidosis-mediated increase in IFN-[gamma]-induced PD-L1 expression on cancer cells as an immune esca...
Acidosis-mediated increase in IFN-[gamma]-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors
About this item
Full title
Author / Creator
Knopf, Philipp , Stowbur, Dimitri , Hoffmann, Sabrina H. L , Hermann, Natalie , Maurer, Andreas , Bucher, Valentina , Poxleitner, Marilena , Tako, Bredi , Sonanini, Dominik , Krishnamachary, Balaji , Sinharay, Sanhita , Fehrenbacher, Birgit , Gonzalez-Menendez, Irene , Reckmann, Felix , Bomze, David , Flatz, Lukas , Kramer, Daniela , Schaller, Ma , Forchhammer, Stephan , Bhujwalla, Zaver M , Quintanilla-Ma , Schulze-Osthoff, Klaus , Pagel, Mark D , Fransen, Marieke F , Röcken, Ma , Ma , Pichler, Bernd J , Ghoreschi, Kamran and Kneilling, Manfred
Publisher
BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L1) expression on cancer cells is mainly regulated by Interferon-gamma (IFN-[gamma]), which induces T cell exh...
Alternative Titles
Full title
Acidosis-mediated increase in IFN-[gamma]-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors
Authors, Artists and Contributors
Author / Creator
Stowbur, Dimitri
Hoffmann, Sabrina H. L
Hermann, Natalie
Maurer, Andreas
Bucher, Valentina
Poxleitner, Marilena
Tako, Bredi
Sonanini, Dominik
Krishnamachary, Balaji
Sinharay, Sanhita
Fehrenbacher, Birgit
Gonzalez-Menendez, Irene
Reckmann, Felix
Bomze, David
Flatz, Lukas
Kramer, Daniela
Schaller, Ma
Forchhammer, Stephan
Bhujwalla, Zaver M
Quintanilla-Ma
Schulze-Osthoff, Klaus
Pagel, Mark D
Fransen, Marieke F
Röcken, Ma
Ma
Pichler, Bernd J
Ghoreschi, Kamran
Kneilling, Manfred
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A776463231
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A776463231
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-023-01900-0
