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Human β-Defensin 3 Inhibition of IP. gingivalis/I LPS-Induced IL-1β Production by BV-2 Microglia thr...

Human β-Defensin 3 Inhibition of IP. gingivalis/I LPS-Induced IL-1β Production by BV-2 Microglia thr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A782089749

Human β-Defensin 3 Inhibition of IP. gingivalis/I LPS-Induced IL-1β Production by BV-2 Microglia through Suppression of Cathepsins B and L

About this item

Full title

Human β-Defensin 3 Inhibition of IP. gingivalis/I LPS-Induced IL-1β Production by BV-2 Microglia through Suppression of Cathepsins B and L

Publisher

MDPI AG

Journal title

Cells (Basel, Switzerland), 2024-02, Vol.13 (3)

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

Cathepsin B (CatB) is thought to be essential for the induction of Porphyromonas gingivalis lipopolysaccharide (Pg LPS)-induced Alzheimer’s disease-like pathologies in mice, including interleukin-1β (IL-1β) production and cognitive decline. However, little is known about the role of CatB in Pg virulence factor-induced IL-1β production by microglia....

Alternative Titles

Full title

Human β-Defensin 3 Inhibition of IP. gingivalis/I LPS-Induced IL-1β Production by BV-2 Microglia through Suppression of Cathepsins B and L

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A782089749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A782089749

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells13030283

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