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Differential Gene Expression following IDHX36/I/IG4R1/I Knockout Is Associated with G-Quadruplex Con...

Differential Gene Expression following IDHX36/I/IG4R1/I Knockout Is Associated with G-Quadruplex Con...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A782090920

Differential Gene Expression following IDHX36/I/IG4R1/I Knockout Is Associated with G-Quadruplex Content and Cancer

About this item

Full title

Differential Gene Expression following IDHX36/I/IG4R1/I Knockout Is Associated with G-Quadruplex Content and Cancer

Publisher

MDPI AG

Journal title

International journal of molecular sciences, 2024-02, Vol.25 (3)

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

G-quadruplexes (G4s) are secondary DNA and RNA structures stabilized by positive cations in a central channel formed by stacked tetrads of Hoogsteen base-paired guanines. G4s form from G-rich sequences across the genome, whose biased distribution in regulatory regions points towards a gene-regulatory role. G4s can themselves be regulated by helicas...

Alternative Titles

Full title

Differential Gene Expression following IDHX36/I/IG4R1/I Knockout Is Associated with G-Quadruplex Content and Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A782090920

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A782090920

Other Identifiers

ISSN

1422-0067

DOI

10.3390/ijms25031753

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