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Deciphering the Crucial Roles of the Quorum-Sensing Transcription Factor SdiA in NADPH Metabolism an...

Deciphering the Crucial Roles of the Quorum-Sensing Transcription Factor SdiA in NADPH Metabolism an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A788242391

Deciphering the Crucial Roles of the Quorum-Sensing Transcription Factor SdiA in NADPH Metabolism and -Equol Production in IEscherichia coli/I Nissle 1917

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Full title

Deciphering the Crucial Roles of the Quorum-Sensing Transcription Factor SdiA in NADPH Metabolism and -Equol Production in IEscherichia coli/I Nissle 1917

Publisher

MDPI AG

Journal title

Antioxidants, 2024-02, Vol.13 (3)

Language

English

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Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

The active metabolite (S)-equol, derived from daidzein by gut microbiota, exhibits superior antioxidative activity compared with its precursor and plays a vital role in human health. As only 25% to 50% of individuals can naturally produce equol when supplied with isoflavone, we engineered probiotic E. coli Nissle 1917 (EcN) to convert dietary isofl...

Alternative Titles

Full title

Deciphering the Crucial Roles of the Quorum-Sensing Transcription Factor SdiA in NADPH Metabolism and -Equol Production in IEscherichia coli/I Nissle 1917

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A788242391

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A788242391

Other Identifiers

ISSN

2076-3921

E-ISSN

2076-3921

DOI

10.3390/antiox13030259

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