Selective Targeting of α[sub.4]β[sub.7]/MAdCAM-1 Axis Suppresses Fibrosis Progression by Reducing Pr...
Selective Targeting of α[sub.4]β[sub.7]/MAdCAM-1 Axis Suppresses Fibrosis Progression by Reducing Proinflammatory T Cell Recruitment to the Liver
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Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
Integrin α[sub.4]β[sub.7]+ T cells perpetuate tissue injury in chronic inflammatory diseases, yet their role in hepatic fibrosis progression remains poorly understood. Here, we report increased accumulation of α[sub.4]β[sub.7]+ T cells in the liver of people with cirrhosis relative to disease controls. Similarly, hepatic fibrosis in the established...
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Full title
Selective Targeting of α[sub.4]β[sub.7]/MAdCAM-1 Axis Suppresses Fibrosis Progression by Reducing Proinflammatory T Cell Recruitment to the Liver
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TN_cdi_gale_infotracmisc_A793567208
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A793567208
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells13090756
