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A novel mouse model for investigating [alpha]-synuclein aggregates in oligodendrocytes: implications...

A novel mouse model for investigating [alpha]-synuclein aggregates in oligodendrocytes: implications...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A795263639

A novel mouse model for investigating [alpha]-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy

About this item

Full title

A novel mouse model for investigating [alpha]-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy

Publisher

BioMed Central Ltd

Journal title

Molecular brain, 2024-05, Vol.17 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

The aggregated alpha-synuclein ([alpha]syn) in oligodendrocytes (OLGs) is one of the pathological hallmarks in multiple system atrophy (MSA). We have previously reported that [alpha]syn accumulates not only in neurons but also in OLGs long after the administration of [alpha]syn preformed fibrils (PFFs) in mice. However, detailed spatial and tempora...

Alternative Titles

Full title

A novel mouse model for investigating [alpha]-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A795263639

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A795263639

Other Identifiers

ISSN

1756-6606

E-ISSN

1756-6606

DOI

10.1186/s13041-024-01104-7

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