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Oncogene-induced matrix reorganization controls [CD8.sup.+] T cell function in the soft-tissue sarco...

Oncogene-induced matrix reorganization controls [CD8.sup.+] T cell function in the soft-tissue sarco...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A797807803

Oncogene-induced matrix reorganization controls [CD8.sup.+] T cell function in the soft-tissue sarcoma microenvironment

About this item

Full title

Oncogene-induced matrix reorganization controls [CD8.sup.+] T cell function in the soft-tissue sarcoma microenvironment

Publisher

American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2024-06, Vol.134 (11)

Language

English

Formats

Publication information

Publisher

American Society for Clinical Investigation

More information

Scope and Contents

Contents

[CD8.sup.+] T cell dysfunction impedes antitumor immunity in solid cancers, but the underlying mechanisms are diverse and poorly understood. Extracellular matrix (ECM) composition has been linked to impaired T cell migration and enhanced tumor progression; however, impacts of individual ECM molecules on T cell function in the tumor microenvironment...

Alternative Titles

Full title

Oncogene-induced matrix reorganization controls [CD8.sup.+] T cell function in the soft-tissue sarcoma microenvironment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A797807803

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A797807803

Other Identifiers

ISSN

0021-9738

DOI

10.1172/JCI167826

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