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Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies

Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A801728701

Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies

About this item

Full title

Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Human heredity, 2024-01, Vol.89 (1), p.32-39

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Abstract
Introduction: The standard way of using tests for compatibility of genetic markers with the Hardy-Weinberg equilibrium (HWE) assumption as a means of quality control in genetic association studies (GAS) is to carry out this step of preliminary data analysis with the sample of non-diseased individuals only. We show that this strategy has...

Alternative Titles

Full title

Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A801728701

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A801728701

Other Identifiers

ISSN

0001-5652

E-ISSN

1423-0062

DOI

10.1159/000537832

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