Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies
Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies
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Basel, Switzerland: S. Karger AG
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English
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Basel, Switzerland: S. Karger AG
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Abstract
Introduction: The standard way of using tests for compatibility of genetic markers with the Hardy-Weinberg equilibrium (HWE) assumption as a means of quality control in genetic association studies (GAS) is to carry out this step of preliminary data analysis with the sample of non-diseased individuals only. We show that this strategy has...
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Implications of the Codominance Model for Hardy-Weinberg Testing in Genetic Association Studies
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TN_cdi_gale_infotracmisc_A801728701
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A801728701
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ISSN
0001-5652
E-ISSN
1423-0062
DOI
10.1159/000537832