Role of the [alpha]C-[beta]4 loop in protein kinase structure and dynamics
Role of the [alpha]C-[beta]4 loop in protein kinase structure and dynamics
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eLife Science Publications, Ltd
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English
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eLife Science Publications, Ltd
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Contents
Although the [alpha]C-[beta]4 loop is a stable feature of all protein kinases, the importance of this motif as a conserved element of secondary structure, as well as its links to the hydrophobic architecture of the kinase core, has been underappreciated. We first review the motif and then describe how it is linked to the hydrophobic spine architect...
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Full title
Role of the [alpha]C-[beta]4 loop in protein kinase structure and dynamics
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TN_cdi_gale_infotracmisc_A818924971
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A818924971
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.91980
