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Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates A[beta] a...

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates A[beta] a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A830102312

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates A[beta] accumulation

About this item

Full title

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates A[beta] accumulation

Publisher

BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2025-03, Vol.13 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Multiple lines of evidence indicate that immune signaling can impact the pathological progression in Alzheimer's disease (AD), including amyloid deposition, tau aggregation, synaptic pathology and neurodegenerative trajectory. In earlier studies, we reported that intracerebral expression of the anti-inflammatory cytokines, Interleukin-10 (Il10) and...

Alternative Titles

Full title

Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates A[beta] accumulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A830102312

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A830102312

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-025-01968-3

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