Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Intracellular pathogens such as Listeria monocytogenes subvert cellular functions through the interaction of bacterial effectors with host components. Here we found that a secreted listerial virulence factor, LntA, could target the chromatin repressor BAHD1 in the host cell nucleus to activate interferon (IFN)-stimulated genes (ISGs). IFN-λ express...
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Full title
Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
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TN_cdi_hal_primary_oai_HAL_cea_00819299v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_cea_00819299v1
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1200120