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Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_cea_00819299v1

Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

About this item

Full title

Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2011-03, Vol.331 (6022), p.1319-1321

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Intracellular pathogens such as Listeria monocytogenes subvert cellular functions through the interaction of bacterial effectors with host components. Here we found that a secreted listerial virulence factor, LntA, could target the chromatin repressor BAHD1 in the host cell nucleus to activate interferon (IFN)-stimulated genes (ISGs). IFN-λ express...

Alternative Titles

Full title

Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_cea_00819299v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_cea_00819299v1

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1200120