Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Key Points
Equilibrated protein homeostasis (referred to as proteostasis) requires the dynamic coordination of efficient folding of newly synthesized proteins, quality control and degradative mechanisms to reduce the load of unfolded and/or misfolded proteins and thereby prevent abnormal protein aggregation. In response to proteostasis perturbat...
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Full title
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
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TN_cdi_hal_primary_oai_HAL_ensl_01074636v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_ensl_01074636v1
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ISSN
1471-003X,1471-0048
E-ISSN
1471-0048,1469-3178
DOI
10.1038/nrn3689
