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Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00091223v1

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

About this item

Full title

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2006-09, Vol.9 (9), p.1134-1141

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Depression is a devastating illness with a lifetime prevalence of up to 20%. The neurotransmitter serotonin or 5-hydroxytryptamine (5-HT) is involved in the pathophysiology of depression and in the effects of antidepressant treatments. However, molecular alterations that underlie the pathology or treatment of depression are still poorly understood....

Alternative Titles

Full title

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_00091223v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00091223v1

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn1749

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