Peptido-Targeting of the Mitochondrial Transition Pore Complex for Therapeutic Apoptosis Induction
Peptido-Targeting of the Mitochondrial Transition Pore Complex for Therapeutic Apoptosis Induction
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Publisher
United Arab Emirates: Bentham Science Publishers Ltd
Journal title
Language
English
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Publisher
United Arab Emirates: Bentham Science Publishers Ltd
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Contents
The permeability transition pore (PTPC), a polyprotein complex, participates in the mitochondrial homeostasis as well as in the mitochondrial phase of the intrinsic pathway of apoptosis. It integrates multiple death signals including alterations of the intracellular milieu, translocation of pro-apoptotic members of the Bax/Bcl-2 family, p53, and vi...
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Full title
Peptido-Targeting of the Mitochondrial Transition Pore Complex for Therapeutic Apoptosis Induction
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_00165302v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00165302v1
Other Identifiers
ISSN
1381-6128
E-ISSN
1873-4286
DOI
10.2174/138161206779010530
