Log in to save to my catalogue

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00315908v1

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage

About this item

Full title

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2008-10, Vol.27 (51), p.6590-6595

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cisplatin is one of the most effectively used chemotherapeutic agents for cancer treatment. However, in humans, important cytotoxic side effects are observed including dose-limiting renal damage and profound gastrointestinal symptomatology. The toxic responses to cisplatin in mice are similar to those in human patients. Here, we evaluated whether t...

Alternative Titles

Full title

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_00315908v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00315908v1

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2008.257