Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage
Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cisplatin is one of the most effectively used chemotherapeutic agents for cancer treatment. However, in humans, important cytotoxic side effects are observed including dose-limiting renal damage and profound gastrointestinal symptomatology. The toxic responses to cisplatin in mice are similar to those in human patients. Here, we evaluated whether t...
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Full title
Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage
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TN_cdi_hal_primary_oai_HAL_hal_00315908v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00315908v1
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2008.257