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Modulation of CD4+ T cell activation by CD95 costimulation

Modulation of CD4+ T cell activation by CD95 costimulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00590749v1

Modulation of CD4+ T cell activation by CD95 costimulation

About this item

Full title

Modulation of CD4+ T cell activation by CD95 costimulation

Publisher

Nature Publishing Group

Journal title

Cell death and differentiation, 2010-11

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

CD95 is a dual-function receptor that exerts pro- or anti-apoptotic effects depending on the cellular context, the state of activation, the signal threshold and the mode of ligation. Here, we report that CD95 engagement modulates TCR/CD3-driven signaling pathways in resting T lymphocytes in a dose-dependent manner. While high doses of immobilized C...

Alternative Titles

Full title

Modulation of CD4+ T cell activation by CD95 costimulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_00590749v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00590749v1

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/cdd.2010.134

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