yeast-based assay identifies drugs active against human mitochondrial disorders
yeast-based assay identifies drugs active against human mitochondrial disorders
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Contents
Due to the lack of relevant animal models, development of effective treatments for human mitochondrial diseases has been limited. Here we establish a rapid, yeast-based assay to screen for drugs active against human inherited mitochondrial diseases affecting ATP synthase, in particular NARP (neuropathy, ataxia, and retinitis pigmentosa) syndrome. T...
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Full title
yeast-based assay identifies drugs active against human mitochondrial disorders
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TN_cdi_hal_primary_oai_HAL_hal_00608540v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00608540v1
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1101478108
