Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different sp...
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
A combination of SAXS, SANS and FRET is used to explore the solution structures of three different nuclear receptor heterodimeric complexes (RXR with RAR, PPARγ or VDR), bound to different target DNA sequences. The work reveals the asymmetric shape of the complexes and the binding of a single coactivator molecule to RXR in each heterodimer.
Nucl...
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Full title
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings
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TN_cdi_hal_primary_oai_HAL_hal_00667005v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00667005v1
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2054