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Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different sp...

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different sp...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00667005v1

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

About this item

Full title

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2011-05, Vol.18 (5), p.564-570

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

A combination of SAXS, SANS and FRET is used to explore the solution structures of three different nuclear receptor heterodimeric complexes (RXR with RAR, PPARγ or VDR), bound to different target DNA sequences. The work reveals the asymmetric shape of the complexes and the binding of a single coactivator molecule to RXR in each heterodimer.
Nucl...

Alternative Titles

Full title

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_00667005v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00667005v1

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.2054

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