Near-fatal tramadol cardiotoxicity in a CYP2D6 ultrarapid metabolizer
Near-fatal tramadol cardiotoxicity in a CYP2D6 ultrarapid metabolizer
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Background
Tramadol is a synthetic, centrally acting analgesic for the treatment of moderate to severe pain. The marketed tramadol is a racemic mixture containing 50% (+)tramadol and 50% (−)tramadol and is mainly metabolized to O-desmethyltramadol (M1) by the cytochrome P450 CYP2D6. Tramadol is generally considered to be devoid of any serious ad...
Alternative Titles
Full title
Near-fatal tramadol cardiotoxicity in a CYP2D6 ultrarapid metabolizer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_00710456v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00710456v1
Other Identifiers
ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-011-1080-x
