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Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension

Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00727663v1

Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension

About this item

Full title

Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2011-01, Vol.91 (1), p.24-32

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Autosomal dominant polycystic kidney disease (ADPKD) is a multisystem disorder characterized by renal, hepatic and pancreatic cyst formation and cardiovascular complications. The condition is caused by mutations in the PKD1 or PKD2 gene. In mice with reduced expression of Pkd1, dissecting aneurysms with prominent media thickening have been seen. To...

Alternative Titles

Full title

Pkd1-inactivation in vascular smooth muscle cells and adaptation to hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_00727663v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00727663v1

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2010.159