Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population
Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Epistatic interactions between mutations play a prominent role in evolutionary theories. Many studies have found that epistasis is widespread, but they have rarely considered beneficial mutations. We analyzed the effects of epistasis on fitness for the first five mutations to fix in an experimental population of Escherichia coli. Epistasis depended...
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Full title
Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population
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TN_cdi_hal_primary_oai_HAL_hal_00800693v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_00800693v1
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1203801
