Circulating Klotho Associates With Cardiovascular Morbidity and Mortality During Hemodialysis
Circulating Klotho Associates With Cardiovascular Morbidity and Mortality During Hemodialysis
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Author / Creator
Marçais, Christophe , Maucort-Boulch, Delphine , Drai, Jocelyne , Dantony, Emmanuelle , Carlier, Marie-Christine , Blond, Emilie , Genet, Leslie , Kuentz, François , Lataillade, Dominique , Legrand, Eric , Moreau-Gaudry, Xavier , Jean, Guillaume , Fouque, Denis , ARNOGENE Project and on behalf of the ARNOGENE Project
Publisher
Washington, DC: Endocrine Society
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Language
English
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Publisher
Washington, DC: Endocrine Society
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Contents
BackgroundKlotho gene was identified as an aging suppressor. In animals, klotho overexpression extends life span, and defective klotho results in rapid aging and early death. The kidney is the main contributor to circulating klotho levels, and, during chronic kidney disease, renal klotho gene expression is drastically reduced in animals and humans...
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Full title
Circulating Klotho Associates With Cardiovascular Morbidity and Mortality During Hemodialysis
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Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_01600112v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01600112v1
Other Identifiers
ISSN
0021-972X
E-ISSN
1945-7197
DOI
10.1210/jc.2017-00104
