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Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut mi...

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut mi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01604354v1

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota

About this item

Full title

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2015-08, Vol.16 (8), p.880-888

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Secretory IgA (SIgA) shapes the gut microbial composition. Pabst and colleagues show that the IgA-secreting plasma cell repertoire, once established, is remarkably resilient to changes in microbial populations that occur upon infection or antibiotic treatment.
Secretory immunoglobulin A (SIgA) shields the gut epithelium from luminal antigens and...

Alternative Titles

Full title

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_01604354v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01604354v1

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3213

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