Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists
Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists
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Author / Creator
Prost, Stéphane , Relouzat, Francis , Spentchian, Marc , Ouzegdouh, Yasmine , Saliba, Joseph , Massonnet, Gérald , Beressi, Jean-Paul , Verhoeyen, Els , Raggueneau, Victoria , Maneglier, Benjamin , Castaigne, Sylvie , Chomienne, Christine , Chrétien, Stany , Rousselot, Philippe and Leboulch, Philippe
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Although imatinib gives good clinical results in chronic myeloid leukaemia (CML), residual disease attributed to quiescent CML stem cells remains in many patients; here glitazones are shown to reduce the pool of CML stem cells and achieve lasting disease eradication in CML patients in combination with imatinib.
The use of glitazone antidiabetics...
Alternative Titles
Full title
Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_01911062v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01911062v1
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature15248
