De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicent...
De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial
About this item
Full title
Author / Creator
Leone, Marc , Bechis, Carole , Baumstarck, Karine , Lefrant, Jean-Yves , Albanèse, Jacques , Jaber, Samir , Lepape, Alain , Constantin, Jean-Michel , Papazian, Laurent , Bruder, Nicolas , Allaouchiche, Bernard , Bézulier, Karine , Antonini, François , Textoris, Julien , Martin, Claude , For the AZUREA Network Investigators and AZUREA Network Investigators
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Background
In patients with severe sepsis, no randomized clinical trial has tested the concept of de-escalation of empirical antimicrobial therapy. This study aimed to compare the de-escalation strategy with the continuation of an appropriate empirical treatment in those patients.
Methods
This was a multicenter non-blinded randomized nonin...
Alternative Titles
Full title
De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial
Authors, Artists and Contributors
Author / Creator
Bechis, Carole
Baumstarck, Karine
Lefrant, Jean-Yves
Albanèse, Jacques
Jaber, Samir
Lepape, Alain
Constantin, Jean-Michel
Papazian, Laurent
Bruder, Nicolas
Allaouchiche, Bernard
Bézulier, Karine
Antonini, François
Textoris, Julien
Martin, Claude
For the AZUREA Network Investigators
AZUREA Network Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_01945691v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_01945691v1
Other Identifiers
ISSN
0342-4642,1432-1238
E-ISSN
1432-1238
DOI
10.1007/s00134-014-3411-8