Log in to save to my catalogue

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02345845v1

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

About this item

Full title

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2017-12, Vol.358 (6369), p.1448-1453

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Reversible detyrosination of α-tubulin is crucial to microtubule dynamics and functions, and defects have been implicated in cancer, brain disorganization, and cardiomyopathies. The identity of the tubulin tyrosine carboxypeptidase (TCP) responsible for detyrosination has remained unclear. We used chemical proteomics with a potent irreversible inhi...

Alternative Titles

Full title

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_02345845v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02345845v1

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aao4165

How to access this item