IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenu...
IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
BPZE1 is a live attenuated
Bordetella pertussis
vaccine for nasal administration to mimic the natural route of infection. Here, we studied the mechanism of BPZE1-induced immunity in the murine nasal cavity in contrast to acellular vaccine (aPV), although both vaccines protected against lung colonization. Transfer of splenocytes or serum from...
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Full title
IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine
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TN_cdi_hal_primary_oai_HAL_hal_02398320v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_02398320v1
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ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/s41385-018-0073-9